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Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation
In mammals, ∼100 deubiquitinases act on ∼20,000 intracellular ubiquitination sites. Deubiquitinases are commonly regarded as constitutively active, with limited regulatory and targeting capacity. The BRCA1-A and BRISC complexes serve in DNA double-strand break repair and immune signaling and contain...
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| Publicado no: | Mol Cell |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cell Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6695476/ https://ncbi.nlm.nih.gov/pubmed/31253574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.002 |
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