Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation

In mammals, ∼100 deubiquitinases act on ∼20,000 intracellular ubiquitination sites. Deubiquitinases are commonly regarded as constitutively active, with limited regulatory and targeting capacity. The BRCA1-A and BRISC complexes serve in DNA double-strand break repair and immune signaling and contain...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Rabl, Julius, Bunker, Richard D., Schenk, Andreas D., Cavadini, Simone, Gill, Mark E., Abdulrahman, Wassim, Andrés-Pons, Amparo, Luijsterburg, Martijn S., Ibrahim, Adel F.M., Branigan, Emma, Aguirre, Jacob D., Marceau, Aimee H., Guérillon, Claire, Bouwmeester, Tewis, Hassiepen, Ulrich, Peters, Antoine H.F.M., Renatus, Martin, Gelman, Laurent, Rubin, Seth M., Mailand, Niels, van Attikum, Haico, Hay, Ronald T., Thomä, Nicolas H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cell Press 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695476/
https://ncbi.nlm.nih.gov/pubmed/31253574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.06.002
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