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SUMOylation and PARylation cooperate to recruit and stabilize SLX4 at DNA damage sites
SUMOylation plays important roles in the DNA damage response. However, whether it is important for interstrand crosslink repair remains unknown. We report that the SLX4 nuclease scaffold protein is regulated by SUMOylation. We have identified three SUMO interaction motifs (SIMs) in SLX4, mutating al...
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| Wydane w: | EMBO Rep |
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| Główni autorzy: | , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BlackWell Publishing Ltd
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388617/ https://ncbi.nlm.nih.gov/pubmed/25722289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201440017 |
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