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Chromatin and the DNA damage response: The cancer connection

The integrity of the human genome is constantly threatened by genotoxic agents that cause DNA damage. Inefficient or inaccurate repair of DNA lesions triggers genome instability and can lead to cancer development or even cell death. Cells counteract the adverse effects of DNA lesions by activating t...

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Detalles Bibliográficos
Publicado en:Mol Oncol
Main Authors: Luijsterburg, Martijn S., van Attikum, Haico
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528312/
https://ncbi.nlm.nih.gov/pubmed/21782533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.06.001
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