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Chromatin and the DNA damage response: The cancer connection

The integrity of the human genome is constantly threatened by genotoxic agents that cause DNA damage. Inefficient or inaccurate repair of DNA lesions triggers genome instability and can lead to cancer development or even cell death. Cells counteract the adverse effects of DNA lesions by activating t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Oncol
Main Authors: Luijsterburg, Martijn S., van Attikum, Haico
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528312/
https://ncbi.nlm.nih.gov/pubmed/21782533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2011.06.001
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