HIV Diversity and Genetic Compartmentalization in Blood and Testes during Suppressive Antiretroviral Therapy

HIV's ability to persist during suppressive antiretroviral therapy is the main barrier to cure. Immune-privileged tissues, such as the testes, may constitute distinctive sites of HIV persistence, but this has been challenging to study in humans. We analyzed the proviral burden and genetics in t...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Miller, Rachel L., Ponte, Rosalie, Jones, Bradley R., Kinloch, Natalie N., Omondi, Fredrick H., Jenabian, Mohammad-Ali, Dupuy, Franck P., Fromentin, Remi, Brassard, Pierre, Mehraj, Vikram, Chomont, Nicolas, Poon, Art F. Y., Joy, Jeffrey B., Brumme, Zabrina L., Routy, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694813/
https://ncbi.nlm.nih.gov/pubmed/31189714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00755-19
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