HIV Diversity and Genetic Compartmentalization in Blood and Testes during Suppressive Antiretroviral Therapy

HIV's ability to persist during suppressive antiretroviral therapy is the main barrier to cure. Immune-privileged tissues, such as the testes, may constitute distinctive sites of HIV persistence, but this has been challenging to study in humans. We analyzed the proviral burden and genetics in t...

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Vydáno v:J Virol
Hlavní autoři: Miller, Rachel L., Ponte, Rosalie, Jones, Bradley R., Kinloch, Natalie N., Omondi, Fredrick H., Jenabian, Mohammad-Ali, Dupuy, Franck P., Fromentin, Remi, Brassard, Pierre, Mehraj, Vikram, Chomont, Nicolas, Poon, Art F. Y., Joy, Jeffrey B., Brumme, Zabrina L., Routy, Jean-Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2019
Témata:
Genetic Diversity and Evolution
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694813/
https://ncbi.nlm.nih.gov/pubmed/31189714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00755-19
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