HIV Diversity and Genetic Compartmentalization in Blood and Testes during Suppressive Antiretroviral Therapy

HIV's ability to persist during suppressive antiretroviral therapy is the main barrier to cure. Immune-privileged tissues, such as the testes, may constitute distinctive sites of HIV persistence, but this has been challenging to study in humans. We analyzed the proviral burden and genetics in t...

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Udgivet i:J Virol
Main Authors: Miller, Rachel L., Ponte, Rosalie, Jones, Bradley R., Kinloch, Natalie N., Omondi, Fredrick H., Jenabian, Mohammad-Ali, Dupuy, Franck P., Fromentin, Remi, Brassard, Pierre, Mehraj, Vikram, Chomont, Nicolas, Poon, Art F. Y., Joy, Jeffrey B., Brumme, Zabrina L., Routy, Jean-Pierre
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Genetic Diversity and Evolution
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694813/
https://ncbi.nlm.nih.gov/pubmed/31189714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00755-19
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