HIV Diversity and Genetic Compartmentalization in Blood and Testes during Suppressive Antiretroviral Therapy

HIV's ability to persist during suppressive antiretroviral therapy is the main barrier to cure. Immune-privileged tissues, such as the testes, may constitute distinctive sites of HIV persistence, but this has been challenging to study in humans. We analyzed the proviral burden and genetics in t...

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Veröffentlicht in:J Virol
Hauptverfasser: Miller, Rachel L., Ponte, Rosalie, Jones, Bradley R., Kinloch, Natalie N., Omondi, Fredrick H., Jenabian, Mohammad-Ali, Dupuy, Franck P., Fromentin, Remi, Brassard, Pierre, Mehraj, Vikram, Chomont, Nicolas, Poon, Art F. Y., Joy, Jeffrey B., Brumme, Zabrina L., Routy, Jean-Pierre
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Genetic Diversity and Evolution
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6694813/
https://ncbi.nlm.nih.gov/pubmed/31189714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00755-19
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