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Latency Reversing Agents Induce Differential Responses in Distinct Memory CD4 T Cell Subsets in Individuals on Antiretroviral Therapy

Latent proviruses persist in central (T(CM)), transitional (T(TM)) and effector (T(EM)) memory cells. We measured the levels of cellular factors involved in HIV gene expression in these subsets. Highest levels of acetylated H4, active NF-κB, and active P-TEFb were measured in T(EM), T(CM) and T(TM)...

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Bibliografiska uppgifter
I publikationen:Cell Rep
Huvudupphovsmän: Pardons, Marion, Fromentin, Rémi, Pagliuzza, Amélie, Routy, Jean-Pierre, Chomont, Nicolas
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943937/
https://ncbi.nlm.nih.gov/pubmed/31775045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.10.101
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