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Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

Clonal expansions occur in the persistent HIV reservoir as shown by the duplication of proviral integration sites. However, the source of the proliferation of HIV-infected cells remains unclear. Here, we analyze the TCR repertoire of single HIV-infected cells harboring translation-competent provirus...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Gantner, Pierre, Pagliuzza, Amélie, Pardons, Marion, Ramgopal, Moti, Routy, Jean-Pierre, Fromentin, Rémi, Chomont, Nicolas
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427996/
https://ncbi.nlm.nih.gov/pubmed/32796830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17898-8
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