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Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

Clonal expansions occur in the persistent HIV reservoir as shown by the duplication of proviral integration sites. However, the source of the proliferation of HIV-infected cells remains unclear. Here, we analyze the TCR repertoire of single HIV-infected cells harboring translation-competent provirus...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Gantner, Pierre, Pagliuzza, Amélie, Pardons, Marion, Ramgopal, Moti, Routy, Jean-Pierre, Fromentin, Rémi, Chomont, Nicolas
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427996/
https://ncbi.nlm.nih.gov/pubmed/32796830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17898-8
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