Single-cell TCR sequencing reveals phenotypically diverse clonally expanded cells harboring inducible HIV proviruses during ART

Clonal expansions occur in the persistent HIV reservoir as shown by the duplication of proviral integration sites. However, the source of the proliferation of HIV-infected cells remains unclear. Here, we analyze the TCR repertoire of single HIV-infected cells harboring translation-competent provirus...

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Publicado en:Nat Commun
Autores principales: Gantner, Pierre, Pagliuzza, Amélie, Pardons, Marion, Ramgopal, Moti, Routy, Jean-Pierre, Fromentin, Rémi, Chomont, Nicolas
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7427996/
https://ncbi.nlm.nih.gov/pubmed/32796830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17898-8
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