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Intramolecular Electrostatic Interactions Contribute to Phospholipase Cβ3 Autoinhibition
Phospholipase Cβ (PLCβ) enzymes regulate second messenger production following the activation of G protein-coupled receptors (GPCRs). Under basal conditions, these enzymes are maintained in an autoinhibited state by multiple elements, including an insertion within the catalytic domain known as the X...
Tallennettuna:
| Julkaisussa: | Cell Signal |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686194/ https://ncbi.nlm.nih.gov/pubmed/31254604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.109349 |
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