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Intramolecular Electrostatic Interactions Contribute to Phospholipase Cβ3 Autoinhibition
Phospholipase Cβ (PLCβ) enzymes regulate second messenger production following the activation of G protein-coupled receptors (GPCRs). Under basal conditions, these enzymes are maintained in an autoinhibited state by multiple elements, including an insertion within the catalytic domain known as the X...
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| Vydáno v: | Cell Signal |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6686194/ https://ncbi.nlm.nih.gov/pubmed/31254604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2019.109349 |
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