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Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

The clinical use of the antibiotic erythromycin (ery) is hampered owing to the spread of resistance genes that are mostly mutating rRNA around the ery binding site at the entrance to the protein exit tunnel. Additional effective resistance mechanisms include deletion or insertion mutations in riboso...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Halfon, Yehuda, Matzov, Donna, Eyal, Zohar, Bashan, Anat, Zimmerman, Ella, Kjeldgaard, Jette, Ingmer, Hanne, Yonath, Ada
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685948/
https://ncbi.nlm.nih.gov/pubmed/31391518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48019-1
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