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Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

The clinical use of the antibiotic erythromycin (ery) is hampered owing to the spread of resistance genes that are mostly mutating rRNA around the ery binding site at the entrance to the protein exit tunnel. Additional effective resistance mechanisms include deletion or insertion mutations in riboso...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Halfon, Yehuda, Matzov, Donna, Eyal, Zohar, Bashan, Anat, Zimmerman, Ella, Kjeldgaard, Jette, Ingmer, Hanne, Yonath, Ada
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685948/
https://ncbi.nlm.nih.gov/pubmed/31391518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48019-1
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