Structure of Pseudomonas aeruginosa ribosomes from an aminoglycoside-resistant clinical isolate

Resistance to antibiotics has become a major threat to modern medicine. The ribosome plays a fundamental role in cell vitality by the translation of the genetic code into proteins; hence, it is a major target for clinically useful antibiotics. We report here the cryo-electron microscopy structures o...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Halfon, Yehuda, Jimenez-Fernandez, Alicia, La Rosa, Ruggero, Espinosa Portero, Rocio, Krogh Johansen, Helle, Matzov, Donna, Eyal, Zohar, Bashan, Anat, Zimmerman, Ella, Belousoff, Matthew, Molin, Søren, Yonath, Ada
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6825255/
https://ncbi.nlm.nih.gov/pubmed/31611393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909831116
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