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A novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism
The increasing appearance of pathogenic bacteria with antibiotic resistance is a global threat. Consequently, clinically available potent antibiotics that are active against multidrug resistant pathogens are becoming exceedingly scarce. Ribosomes are a main target for antibiotics, and hence are an o...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154188/ https://ncbi.nlm.nih.gov/pubmed/27958389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39004 |
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