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Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant
The clinical use of the antibiotic erythromycin (ery) is hampered owing to the spread of resistance genes that are mostly mutating rRNA around the ery binding site at the entrance to the protein exit tunnel. Additional effective resistance mechanisms include deletion or insertion mutations in riboso...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6685948/ https://ncbi.nlm.nih.gov/pubmed/31391518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48019-1 |
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