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Exit tunnel modulation as resistance mechanism of S. aureus erythromycin resistant mutant

The clinical use of the antibiotic erythromycin (ery) is hampered owing to the spread of resistance genes that are mostly mutating rRNA around the ery binding site at the entrance to the protein exit tunnel. Additional effective resistance mechanisms include deletion or insertion mutations in riboso...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Halfon, Yehuda, Matzov, Donna, Eyal, Zohar, Bashan, Anat, Zimmerman, Ella, Kjeldgaard, Jette, Ingmer, Hanne, Yonath, Ada
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685948/
https://ncbi.nlm.nih.gov/pubmed/31391518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-48019-1
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