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Stromal iodothyronine deiodinase 2 (DIO2) promotes the growth of intestinal tumors in Apc (Δ716) mutant mice
Iodothyronine deiodinase 2 (DIO2) converts the prohormone thyroxine (T4) to bioactive T3 in peripheral tissues and thereby regulates local thyroid hormone (TH) levels. Although epidemiologic studies suggest the contribution of TH to the progression of colorectal cancer (CRC), the role of DIO2 in CRC...
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| 出版年: | Cancer Sci |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6676103/ https://ncbi.nlm.nih.gov/pubmed/31215118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14100 |
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