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Life Without the Iodothyronine Deiodinases

The three iodothyronine deiodinases (D1, D2, and D3) play major roles in determining the tissue and cellular content of the active thyroid hormone, T(3). The D1 and D2 5′-deiodinate T(4) to T(3) and the D3 5-deiodinates T(4) and T(3) to inactive forms. 5′-Deiodinase-deficient mice (D1/D2KO) have a m...

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Autors principals: Galton, Valerie Anne, de Waard, Ellis, Parlow, Albert F., St Germain, Donald L., Hernandez, Arturo
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164924/
https://ncbi.nlm.nih.gov/pubmed/24949664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1184
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