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Life Without the Iodothyronine Deiodinases

The three iodothyronine deiodinases (D1, D2, and D3) play major roles in determining the tissue and cellular content of the active thyroid hormone, T(3). The D1 and D2 5′-deiodinate T(4) to T(3) and the D3 5-deiodinates T(4) and T(3) to inactive forms. 5′-Deiodinase-deficient mice (D1/D2KO) have a m...

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Bibliografske podrobnosti
Main Authors: Galton, Valerie Anne, de Waard, Ellis, Parlow, Albert F., St Germain, Donald L., Hernandez, Arturo
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164924/
https://ncbi.nlm.nih.gov/pubmed/24949664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1184
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