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Life Without the Iodothyronine Deiodinases
The three iodothyronine deiodinases (D1, D2, and D3) play major roles in determining the tissue and cellular content of the active thyroid hormone, T(3). The D1 and D2 5′-deiodinate T(4) to T(3) and the D3 5-deiodinates T(4) and T(3) to inactive forms. 5′-Deiodinase-deficient mice (D1/D2KO) have a m...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Endocrine Society
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4164924/ https://ncbi.nlm.nih.gov/pubmed/24949664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1184 |
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