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Life Without the Iodothyronine Deiodinases

The three iodothyronine deiodinases (D1, D2, and D3) play major roles in determining the tissue and cellular content of the active thyroid hormone, T(3). The D1 and D2 5′-deiodinate T(4) to T(3) and the D3 5-deiodinates T(4) and T(3) to inactive forms. 5′-Deiodinase-deficient mice (D1/D2KO) have a m...

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Bibliografiske detaljer
Main Authors: Galton, Valerie Anne, de Waard, Ellis, Parlow, Albert F., St Germain, Donald L., Hernandez, Arturo
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4164924/
https://ncbi.nlm.nih.gov/pubmed/24949664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1184
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