Human Type 1 Iodothyronine Deiodinase (DIO1) Mutations Cause Abnormal Thyroid Hormone Metabolism

Background: Iodothyronine deiodinase-1 (D1) selenoenzyme regulates the systemic supply of active thyroid hormone (TH). Transient decrease in D1 enzymatic activity is clinically relevant and adaptive in nonthyroidal illness such as fasting or acute illness. However, DIO1 gene defects have not been re...

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Bibliografiske detaljer
Udgivet i:Thyroid
Main Authors: França, Monica M., German, Alina, Fernandes, Gustavo W., Liao, Xiao-Hui, Bianco, Antonio C., Refetoff, Samuel, Dumitrescu, Alexandra M.
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc., publishers 2021
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Original Studies
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7891200/
https://ncbi.nlm.nih.gov/pubmed/32718224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2020.0253
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