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Stromal iodothyronine deiodinase 2 (DIO2) promotes the growth of intestinal tumors in Apc (Δ716) mutant mice
Iodothyronine deiodinase 2 (DIO2) converts the prohormone thyroxine (T4) to bioactive T3 in peripheral tissues and thereby regulates local thyroid hormone (TH) levels. Although epidemiologic studies suggest the contribution of TH to the progression of colorectal cancer (CRC), the role of DIO2 in CRC...
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| Publicado no: | Cancer Sci |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6676103/ https://ncbi.nlm.nih.gov/pubmed/31215118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14100 |
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