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Serine and 1-carbon metabolism are required for HIF-mediated protection against retinopathy of prematurity
We determined which metabolic pathways are activated by hypoxia-inducible factor 1–mediated (HIF-1–mediated) protection against oxygen-induced retinopathy (OIR) in newborn mice, the experimental correlate to retinopathy of prematurity, a leading cause of infant blindness. HIF-1 coordinates the chang...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6675544/ https://ncbi.nlm.nih.gov/pubmed/31341109 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.129398 |
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