Impaired Ribosomal Biogenesis by Noncanonical Degradation of β-Catenin during Hyperammonemia

Increased ribosomal biogenesis occurs during tissue hypertrophy, but whether ribosomal biogenesis is impaired during atrophy is not known. We show that hyperammonemia, which occurs in diverse chronic disorders, impairs protein synthesis as a result of decreased ribosomal content and translational ca...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Davuluri, Gangarao, Giusto, Michela, Chandel, Rajeev, Welch, Nicole, Alsabbagh, Khaled, Kant, Sashi, Kumar, Avinash, Kim, Adam, Gangadhariah, Mahesha, Ghosh, Prabar K., Tran, Uyen, Krajcik, Daniel M., Vasu, Kommireddy, DiDonato, Anthony J., DiDonato, Joseph A., Willard, Belinda, Monga, Satdarshan P., Wang, Yuxin, Fox, Paul L., Stark, George R., Wessely, Oliver, Esser, Karyn A., Dasarathy, Srinivasan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6664607/
https://ncbi.nlm.nih.gov/pubmed/31138664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00451-18
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares