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Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy

Protein synthesis and autophagy are regulated by cellular ATP content. We tested the hypothesis that mitochondrial dysfunction, including generation of reactive oxygen species (ROS), contributes to impaired protein synthesis and increased proteolysis resulting in tissue atrophy in a comprehensive ar...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Free Radic Biol Med
Main Authors: Kumar, Avinash, Davuluri, Gangarao, Welch, Nicole, Kim, Adam, Gangadhariah, Mahesha, Allawy, Allawy, Priyadarshini, Anupama, McMullen, Megan R, Sandlers, Yana, Willard, Belinda, Hoppel, Charles L, Nagy, Laura E, Dasarathy, Srinivasan
פורמט: Artigo
שפה:Inglês
יצא לאור: 2019
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910229/
https://ncbi.nlm.nih.gov/pubmed/31574345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.09.031
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