Alcohol-induced autophagy contributes to loss in skeletal muscle mass

Patients with alcoholic cirrhosis and hepatitis have severe muscle loss. Since ethanol impairs skeletal muscle protein synthesis but does not increase ubiquitin proteasome-mediated proteolysis, we investigated whether alcohol-induced autophagy contributes to muscle loss. Autophagy induction was stud...

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Detalhes bibliográficos
Main Authors: Thapaliya, Samjhana, Runkana, Ashok, McMullen, Megan R, Nagy, Laura E, McDonald, Christine, Prasad, Sathyamangla V Naga, Dasarathy, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Translational Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091154/
https://ncbi.nlm.nih.gov/pubmed/24492484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.27918
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