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Oxidative stress mediates ethanol-induced skeletal muscle mitochondrial dysfunction and dysregulated protein synthesis and autophagy

Protein synthesis and autophagy are regulated by cellular ATP content. We tested the hypothesis that mitochondrial dysfunction, including generation of reactive oxygen species (ROS), contributes to impaired protein synthesis and increased proteolysis resulting in tissue atrophy in a comprehensive ar...

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Bibliografische gegevens
Gepubliceerd in:Free Radic Biol Med
Hoofdauteurs: Kumar, Avinash, Davuluri, Gangarao, Welch, Nicole, Kim, Adam, Gangadhariah, Mahesha, Allawy, Allawy, Priyadarshini, Anupama, McMullen, Megan R, Sandlers, Yana, Willard, Belinda, Hoppel, Charles L, Nagy, Laura E, Dasarathy, Srinivasan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6910229/
https://ncbi.nlm.nih.gov/pubmed/31574345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.09.031
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