Hyperammonemia results in reduced muscle function independent of muscle mass

The mechanism of the nearly universal decreased muscle strength in cirrhosis is not known. We evaluated whether hyperammonemia in cirrhosis causes contractile dysfunction independent of reduced skeletal muscle mass. Maximum grip strength and muscle fatigue response were determined in cirrhotic patie...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: McDaniel, John, Davuluri, Gangarao, Hill, Elizabeth Ann, Moyer, Michelle, Runkana, Ashok, Prayson, Richard, van Lunteren, Erik, Dasarathy, Srinivasan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Systems Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971815/
https://ncbi.nlm.nih.gov/pubmed/26635319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00322.2015
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