Hyperammonemia results in reduced muscle function independent of muscle mass

The mechanism of the nearly universal decreased muscle strength in cirrhosis is not known. We evaluated whether hyperammonemia in cirrhosis causes contractile dysfunction independent of reduced skeletal muscle mass. Maximum grip strength and muscle fatigue response were determined in cirrhotic patie...

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Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: McDaniel, John, Davuluri, Gangarao, Hill, Elizabeth Ann, Moyer, Michelle, Runkana, Ashok, Prayson, Richard, van Lunteren, Erik, Dasarathy, Srinivasan
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2015
Matèries:
Systems Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971815/
https://ncbi.nlm.nih.gov/pubmed/26635319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00322.2015
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