Hyperammonemia results in reduced muscle function independent of muscle mass

The mechanism of the nearly universal decreased muscle strength in cirrhosis is not known. We evaluated whether hyperammonemia in cirrhosis causes contractile dysfunction independent of reduced skeletal muscle mass. Maximum grip strength and muscle fatigue response were determined in cirrhotic patie...

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Bibliografske podrobnosti
izdano v:Am J Physiol Gastrointest Liver Physiol
Main Authors: McDaniel, John, Davuluri, Gangarao, Hill, Elizabeth Ann, Moyer, Michelle, Runkana, Ashok, Prayson, Richard, van Lunteren, Erik, Dasarathy, Srinivasan
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2015
Teme:
Systems Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971815/
https://ncbi.nlm.nih.gov/pubmed/26635319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00322.2015
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