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Engineering proteins for allosteric control by light or ligands
Control of protein activity in living cells can reveal the role of spatio-temporal dynamics in signaling circuits. Protein analogs with engineered allosteric responses can be particularly effective, as they can replace endogenous proteins with minimum perturbation of native interactions. However, it...
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| Udgivet i: | Nat Protoc |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6648709/ https://ncbi.nlm.nih.gov/pubmed/31076662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0165-3 |
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