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Engineered allosteric activation of kinases in living cells
Studies of cellular and tissue dynamics benefit greatly from tools that can control protein activity with specificity and precise timing in living systems. We describe here a new approach to confer allosteric regulation specifically on the catalytic activity of kinases. A highly conserved portion of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902629/ https://ncbi.nlm.nih.gov/pubmed/20581846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1639 |
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