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Engineering proteins for allosteric control by light or ligands

Control of protein activity in living cells can reveal the role of spatio-temporal dynamics in signaling circuits. Protein analogs with engineered allosteric responses can be particularly effective, as they can replace endogenous proteins with minimum perturbation of native interactions. However, it...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Protoc
Päätekijät: Dagliyan, Onur, Dokholyan, Nikolay V., Hahn, Klaus M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648709/
https://ncbi.nlm.nih.gov/pubmed/31076662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-019-0165-3
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