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Allosteric activation of kinases: Design and application of RapR kinases
Here we describe a method for the engineered regulation of protein kinases in living cells, the design and application of RapR (rapamycin regulated) kinases. The RapR kinase method enables activation of kinases with high specificity and precise temporal control. Insertion of an engineered allosteric...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269071/ https://ncbi.nlm.nih.gov/pubmed/22161545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471143030.cb1413s53 |
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