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Phenotypic screening combined with machine learning for efficient identification of breast cancer-selective therapeutic targets
The lack of functional understanding of most mutations in cancer, combined with the nondruggability of most proteins, challenge genomics-based identification of oncology drug targets. We implemented a machine learning-based approach (idTRAX), which relates cell-based screening of small-molecule comp...
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| Foilsithe in: | Cell Chem Biol |
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| Main Authors: | , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
2019
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6642004/ https://ncbi.nlm.nih.gov/pubmed/31056464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2019.03.011 |
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