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Multiobjective optimization identifies cancer-selective combination therapies
Combinatorial therapies are required to treat patients with advanced cancers that have become resistant to monotherapies through rewiring of redundant pathways. Due to a massive number of potential drug combinations, there is a need for systematic approaches to identify safe and effective combinatio...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7793282/ https://ncbi.nlm.nih.gov/pubmed/33370253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008538 |
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