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A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening
Accurate quantification of drug effects is crucial for identifying pharmaceutically actionable cancer vulnerabilities. Current cell viability-based measurements often lead to biased response estimates due to varying growth rates and experimental artifacts that explain part of the inconsistency in hi...
Uloženo v:
| Vydáno v: | Commun Biol |
|---|---|
| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2020
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6978361/ https://ncbi.nlm.nih.gov/pubmed/31974521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0765-z |
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