Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity

Mitochondrial complex I dysfunction is the most common respiratory chain defect in human disorders and a hotspot for neurodegenerative diseases. Amyloid precursor protein (APP) and its non-amyloidogenic processing products, in particular soluble APP α (sAPPα), have been shown to provide neuroprotect...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Cimdins, Kathryn, Waugh, Hayley S., Chrysostomou, Vicki, Lopez Sanchez, M. Isabel G., Johannsen, Vanessa A., Cook, Mark J., Crowston, Jonathan G., Hill, Andrew F., Duce, James A., Bush, Ashley I., Trounce, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614131/
https://ncbi.nlm.nih.gov/pubmed/30612335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1460-7
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