Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity

Mitochondrial complex I dysfunction is the most common respiratory chain defect in human disorders and a hotspot for neurodegenerative diseases. Amyloid precursor protein (APP) and its non-amyloidogenic processing products, in particular soluble APP α (sAPPα), have been shown to provide neuroprotect...

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發表在:Mol Neurobiol
Main Authors: Cimdins, Kathryn, Waugh, Hayley S., Chrysostomou, Vicki, Lopez Sanchez, M. Isabel G., Johannsen, Vanessa A., Cook, Mark J., Crowston, Jonathan G., Hill, Andrew F., Duce, James A., Bush, Ashley I., Trounce, Ian A.
格式: Artigo
語言:Inglês
出版: Springer US 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6614131/
https://ncbi.nlm.nih.gov/pubmed/30612335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1460-7
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