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Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice
Proteolytic cleavage of the amyloid precursor protein (APP) into the Aβ peptide has been an extensively researched mechanism for Alzheimer’s disease, but the normal function of the protein is less understood. APP functions to regulate neuronal iron content by stabilizing the surface presentation of...
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| Pubblicato in: | Neurotherapeutics |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer International Publishing
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6277293/ https://ncbi.nlm.nih.gov/pubmed/30112699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-018-0656-x |
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