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Amyloid precursor protein‐mediated mitochondrial regulation and Alzheimer's disease

Despite clear evidence of a neuroprotective physiological role of amyloid precursor protein (APP) and its non‐amyloidogenic processing products, APP has been investigated mainly in animal and cellular models of amyloid pathology in the context of Alzheimer's disease. The rare familial mutations...

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Publicat a:Br J Pharmacol
Autors principals: Lopez Sanchez, M Isabel G, van Wijngaarden, Peter, Trounce, Ian A
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715589/
https://ncbi.nlm.nih.gov/pubmed/30471088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14554
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