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Amyloid Precursor Protein Processing and Alzheimer’s Disease
Alzheimer’s disease (AD), the leading cause of dementia worldwide, is characterized by the accumulation of the β-amyloid peptide (Aβ) within the brain along with hyperphosphorylated and cleaved forms of the microtubule-associated protein tau. Genetic, biochemical, and behavioral research suggest tha...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174086/ https://ncbi.nlm.nih.gov/pubmed/21456963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-neuro-061010-113613 |
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