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Platelet amyloid precursor protein processing: A bio-marker for Alzheimer's disease

The amyloid precursor protein (APP) in brain is processed either by an amyloidogenic pathway by β-secretase and γ-secretase to yield Aβ (β-amyloid 4 kDa) peptide or by α-secretase within the β-amyloid domain to yield non-amyloidogenic products. We have studied blood platelet levels of a 22-kDa fragm...

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Détails bibliographiques
Auteurs principaux: Tang, Kun, Hynan, Linda S., Baskin, Fred, Rosenberg, Roger N.
Format: Artigo
Langue:Inglês
Publié: 2005
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479090/
https://ncbi.nlm.nih.gov/pubmed/16256140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2005.09.002
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