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Platelet amyloid precursor protein processing: A bio-marker for Alzheimer's disease
The amyloid precursor protein (APP) in brain is processed either by an amyloidogenic pathway by β-secretase and γ-secretase to yield Aβ (β-amyloid 4 kDa) peptide or by α-secretase within the β-amyloid domain to yield non-amyloidogenic products. We have studied blood platelet levels of a 22-kDa fragm...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479090/ https://ncbi.nlm.nih.gov/pubmed/16256140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2005.09.002 |
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