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N-terminal degradation activates the NLRP1B inflammasome
Intracellular pathogens and danger signals trigger the formation of inflammasomes, which activate inflammatory caspases and induce pyroptosis. The anthrax lethal factor metalloprotease and small-molecule DPP8/9 inhibitors both activate the NLRP1B inflammasome, but the molecular mechanism of NLRP1B a...
Gorde:
| Argitaratua izan da: | Science |
|---|---|
| Egile Nagusiak: | , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2019
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6610862/ https://ncbi.nlm.nih.gov/pubmed/30872531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau1208 |
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