Caricamento...
A Liquid Chromatography/Mass Spectrometry Method for Screening Disulfide Tethering Fragments
We report the refinement of a high-throughput, liquid chromatography/mass spectrometry (LC/MS)–based screening method for the identification of covalent small-molecule binders to proteins. Using a custom library of 1600 disulfide-capped fragments targeting surface cysteine residues, we optimize samp...
Salvato in:
| Pubblicato in: | SLAS Discov |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609441/ https://ncbi.nlm.nih.gov/pubmed/28945980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217732072 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|