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Tethering in RNA: An RNA-Binding Fragment Discovery Tool

Tethering has been extensively used to study small molecule interactions with proteins through reversible disulfide bond forming reactions to cysteine residues. We describe the adaptation of Tethering to the study of small molecule binding to RNA using a thiol-containing adenosine analog (A(SH)). Am...

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書誌詳細
出版年:Molecules
主要な著者: Tran, Kiet, Arkin, Michelle R., Beal, Peter A.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760646/
https://ncbi.nlm.nih.gov/pubmed/25749683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20034148
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