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Tethering in RNA: An RNA-Binding Fragment Discovery Tool

Tethering has been extensively used to study small molecule interactions with proteins through reversible disulfide bond forming reactions to cysteine residues. We describe the adaptation of Tethering to the study of small molecule binding to RNA using a thiol-containing adenosine analog (A(SH)). Am...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Tran, Kiet, Arkin, Michelle R., Beal, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760646/
https://ncbi.nlm.nih.gov/pubmed/25749683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules20034148
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