Lanean...
A Liquid Chromatography/Mass Spectrometry Method for Screening Disulfide Tethering Fragments
We report the refinement of a high-throughput, liquid chromatography/mass spectrometry (LC/MS)–based screening method for the identification of covalent small-molecule binders to proteins. Using a custom library of 1600 disulfide-capped fragments targeting surface cysteine residues, we optimize samp...
Gorde:
| Argitaratua izan da: | SLAS Discov |
|---|---|
| Egile Nagusiak: | , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2017
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609441/ https://ncbi.nlm.nih.gov/pubmed/28945980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217732072 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|